University Student Government is the highest student governing body of the University of Science and Technology of Southern Philippines- CDO Campus. The student government promotes holistic growth and development- an ability which is vitally important in order for its constituents to be capable in facing the demands and challenges of everyday lives.

Curricular Student Organizations are aligned with academic disciplines and provide support and enrichment activities related to specific fields of study, such as the Student Council of Engineering and Architecture and the Student Council of Science and Mathematics. These organizations enhance student's learning in a certain academic discipline through the conduct of special lecture series, symposia, exhibits and other learning activities.

Non-Curricular Student Organizations focus on extracurricular interests such as arts, culture, leadership, and community service, including the University City Scholars - USTP, and the Google Developer Student Clubs USTP. The Arts and Culture Division falls into the category of non-curricular student organization includes groups dedicated to artistic and cultural expression, such as the Gintong Amihan Dance Troupe, and Playmakers.